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John Holmes - 06 Jul 2009 11:44 GMT http://www.abc.net.au/news/stories/2009/07/06/2618426.htm?section=justin Coffee 'could reverse Alzheimer's effects'
US researchers suggest that an increased caffeine intake cannot only prevent Alzheimer's disease, but also reverse its effects, in mice at least.
Comments?
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Donna Richoux - 06 Jul 2009 12:25 GMT > http://www.abc.net.au/news/stories/2009/07/06/2618426.htm?section=justin > Coffee 'could reverse Alzheimer's effects' [quoted text clipped - 4 lines] > > Comments? Yes, it's awkward. I suppose some editor or spelling checker said that "can not" must be "cannot," even though the "not" goes with "only" here. Not-only.
"Could not only" doesn't fall victim to that problem, and sounds a bit better with "suggest."
There's also "not only can" and "not only could."
[But a canner can't can a can, can he?]
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Peter Duncanson (BrE) - 06 Jul 2009 12:38 GMT >http://www.abc.net.au/news/stories/2009/07/06/2618426.htm?section=justin > Coffee 'could reverse Alzheimer's effects' [quoted text clipped - 4 lines] > >Comments? I would certainly replace "cannot" by "can not" because the "not" goes with "only" rather than "can".
 Signature Peter Duncanson, UK (in alt.usage.english)
HVS - 06 Jul 2009 12:41 GMT On 06 Jul 2009, John Holmes wrote
> http://www.abc.net.au/news/stories/2009/07/06/2618426.htm?section > =justin [quoted text clipped - 6 lines] > > Comments? Made me think about caffeine, and something I've only recently thought about.
We tend to take "paracetamol plus" for pain relief at our house, which have 500mg of paracetamol and 65mg of caffeine in them.
Caffeine content in coffee varies tremendously, but a bit of internet poking comes up with mean figures for caffeine content (for a 150ml/5oz cup of coffee) of around 115mg for drip, 80mg for percolated, and 65mg for instant.
So 2 paracetamol-plus tablets has quite a hit of caffeine, which hadn't really occurred to me..
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Pat Durkin - 06 Jul 2009 16:44 GMT > On 06 Jul 2009, John Holmes wrote > [quoted text clipped - 22 lines] > So 2 paracetamol-plus tablets has quite a hit of caffeine, which > hadn't really occurred to me.. One guest medical commentator (I know the anchor called her "Dr Ashton", but I swear there was a caption when the woman first appeared that said "medical student"...so you takes your pick) announced today that the caffeine was tested with the equivalent of 500 mg on "mice engineered for Alzheimer's (or some kinds of dementia), and the context was to explain that the morning cup of coffee was not prevention, but "theapeutic treatment".
In the meantime, warnings about dosage of acetominophen (I think that is paracetamol in UK, isn't it?), because the drug has been related to higher frequency of liver failure. Oh, shucks, now I have forgotten the third drug scare/warning about. Do I need more caffeine?
Peter Duncanson (BrE) - 06 Jul 2009 18:07 GMT >In the meantime, warnings about dosage of acetominophen (I think that is >paracetamol in UK, isn't it?) Yes.
 Signature Peter Duncanson, UK (in alt.usage.english)
Chuck Riggs - 07 Jul 2009 12:13 GMT >> On 06 Jul 2009, John Holmes wrote >> [quoted text clipped - 36 lines] >Oh, shucks, now I have forgotten the third drug scare/warning about. Do >I need more caffeine? I have found that codeine-based painkillers, available OTC in the British Isles under the brand name of Solpadeine, for one, are more effective. As with any drug, there are downsides. This article from "The Irish Independent", which I haven't read, discusses some of them:
http://www.independent.ie/national-news/patients-warned-to-consult-gps-over-code ine-painkillers-134600.html
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Regards,
Chuck Riggs, who speaks AmE, lives near Dublin, Ireland and usually spells in BrE
Peter Duncanson (BrE) - 07 Jul 2009 13:10 GMT >>> On 06 Jul 2009, John Holmes wrote >>> [quoted text clipped - 43 lines] > >http://www.independent.ie/national-news/patients-warned-to-consult-gps-over-code ine-painkillers-134600.html In the UK Solpadeine is available OTC but only from pharmacies.
Straight codeine tablets used to be available but were discontinued for safety reasons.
Solpadeine tablets are normal strength paracetamol tablets with added codeine.
(The spellchecker wanted to change Solpadeine to Gladdened, which seems somewhat appropriate.)
 Signature Peter Duncanson, UK (in alt.usage.english)
the Omrud - 07 Jul 2009 13:26 GMT >> I have found that codeine-based painkillers, available OTC in the >> British Isles under the brand name of Solpadeine, for one, are more [quoted text clipped - 13 lines] > (The spellchecker wanted to change Solpadeine to Gladdened, which seems > somewhat appropriate.) The generic name is co-codamol. It seems that there are different strength combinations available, but the higher dose tablets are Prescription Only.
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Amethyst Deceiver - 07 Jul 2009 14:12 GMT > >> I have found that codeine-based painkillers, available OTC in the > >> British Isles under the brand name of Solpadeine, for one, are more [quoted text clipped - 17 lines] > strength combinations available, but the higher dose tablets are > Prescription Only. Mind you, you can now get paracetamol and dihydrocodeine OTC - that used to be called co-dydramol. I think that's stronger than paracetamol and codeine. It certainly feels that way to me.
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the Omrud - 07 Jul 2009 14:29 GMT >>>> I have found that codeine-based painkillers, available OTC in the >>>> British Isles under the brand name of Solpadeine, for one, are more [quoted text clipped - 19 lines] > to be called co-dydramol. I think that's stronger than paracetamol and > codeine. It certainly feels that way to me. Naked DHC is strictly controlled - it has a significant recreational use and there's a max 5 years for illegal possession. Presumably the paracetamol must make it unsuitable for non-pain-relief purposes.
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Peter Duncanson (BrE) - 07 Jul 2009 14:59 GMT >>>>> I have found that codeine-based painkillers, available OTC in the >>>>> British Isles under the brand name of Solpadeine, for one, are more [quoted text clipped - 23 lines] >and there's a max 5 years for illegal possession. Presumably the >paracetamol must make it unsuitable for non-pain-relief purposes. The paracetamol can introduce a self-limiting effect. If the user takes massive amounts of paracetamol and dihydrocodeine he/she might go into a paracetamol-associated coma. This will prevent the user taking any more tablets. If this leads to death the user's abuse problem is solved permanently.
(Other methods of preventing abuse are preferred.)
 Signature Peter Duncanson, UK (in alt.usage.english)
Robin Bignall - 07 Jul 2009 22:17 GMT >>>>>> I have found that codeine-based painkillers, available OTC in the >>>>>> British Isles under the brand name of Solpadeine, for one, are more [quoted text clipped - 29 lines] >tablets. If this leads to death the user's abuse problem is solved >permanently. That's a fairly drastic way of avoiding Alzheimer's. I'll stick with er ... wotsitsname, the brown liquid that's served in a wotsitsname.
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the Omrud - 07 Jul 2009 22:56 GMT >>> Naked DHC is strictly controlled - it has a significant recreational use >>> and there's a max 5 years for illegal possession. Presumably the [quoted text clipped - 7 lines] > That's a fairly drastic way of avoiding Alzheimer's. I'll stick with > er ... wotsitsname, the brown liquid that's served in a wotsitsname. Gravy?
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Roland Hutchinson - 08 Jul 2009 03:30 GMT >>> The paracetamol can introduce a self-limiting effect. If the user takes >>> massive amounts of paracetamol and dihydrocodeine he/she might go into a [quoted text clipped - 4 lines] >> That's a fairly drastic way of avoiding Alzheimer's. I'll stick with >> er ... wotsitsname, the brown liquid that's served in a wotsitsname. Robert Bannister wrote:
> Beer?
> Gravy? I figure as long as I can still tell the difference, I'm okay.
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Robert Bannister - 08 Jul 2009 01:55 GMT > That's a fairly drastic way of avoiding Alzheimer's. I'll stick with > er ... wotsitsname, the brown liquid that's served in a wotsitsname. Beer?
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Rob Bannister
Paul Wolff - 07 Jul 2009 15:27 GMT >Amethyst Deceiver wrote: >>>> [quoted text clipped - 24 lines] >use and there's a max 5 years for illegal possession. Presumably the >paracetamol must make it unsuitable for non-pain-relief purposes. Paracetamol gets up my nose.
There was a case for hyphens: you can now get paracetamol-and-dihydrocodeine OTC or brackets of some flavour: you can now get (paracetamol and dihydrocodeine) OTC or an added word: you can now get compound paracetamol and dihydrocodeine OTC back there, since the original didn't warn innocents like me that the named items weren't being listed separately.
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the Omrud - 07 Jul 2009 15:35 GMT >> Amethyst Deceiver wrote: >>>>> [quoted text clipped - 25 lines] >> > Paracetamol gets up my nose. Er, no, those who know about such things tell me that it's injected. The DHC, not the paracetamol.
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LFS - 07 Jul 2009 18:16 GMT > Paracetamol gets up my nose. <odd mental picture> I assume you crush the tablets first?
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Adam Funk - 07 Jul 2009 18:57 GMT >> Paracetamol gets up my nose. > ><odd mental picture> I assume you crush the tablets first? <odd mental picture> Rolling up a £20?
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Paul Wolff - 07 Jul 2009 20:38 GMT >On 2009-07-07, LFS wrote: > [quoted text clipped - 3 lines] > ><odd mental picture> Rolling up a £20? Unfortunately, I hadn't a riposte up my sleeve when first I posted.
I'm averse to paracetamol.
But cue a little ditty:
A poster who answers to Wol ff Had a habit exceedingly droll: When asked "Wazza marra?" He would say "Where's the para acetamidophenol?"
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Mark Brader - 07 Jul 2009 23:54 GMT Paul Wolff posts a little ditty:
> A poster who answers to Wol > ff Had a habit exceedingly droll: > When asked "Wazza marra?" > He would say "Where's the para > acetamidophenol?" The last line doesn't scan. But what I'm mostly curious about is how that "ff" got in there before "Had".
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Peter Duncanson (BrE) - 08 Jul 2009 00:21 GMT >Paul Wolff posts a little ditty: > [quoted text clipped - 6 lines] >The last line doesn't scan. But what I'm mostly curious about is >how that "ff" got in there before "Had". The author's name is split over two lines so that the first line can end in "-ol"
 Signature Peter Duncanson, UK (in alt.usage.english)
Mark Brader - 08 Jul 2009 04:12 GMT Mark Brader:
>> ...what I'm mostly curious about is how that "ff" got in there before "Had". Peter Duncanson:
> The author's name is split over two lines so that the first line can end > in "-ol" Oh! So it was just a case of a missing hyphen. Sorry for the whoosh, P- aul.
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Paul Wolff - 08 Jul 2009 09:58 GMT >Paul Wolff posts a little ditty: > [quoted text clipped - 5 lines] > >The last line doesn't scan. The syllable count is irregular throughout, but a limerick is nothing if not flexible.
I think you have to run together two lightly stressed syllables at the start of line 2 while ignoring the vowel-less entry ("ff Had a") and do something similar for line 4 ("He'd") if you want them to match each other. Then ignore the lack of a short stress before "acet-" in line 5: it's replaced by a slight stop to avoid eliding para-acet.
For declamatory purposes, it works for me. Let's use ~ for a light stress, and - to denote heavy stress.
~ - ~ ~ - ~ ~ - A poster who answers to Wol
~ ~ - ~ ~ - ~ ~ - ff Had a habit exceedingly droll:
~ - ~ ~ - ~ When asked "Wazza marra?"
~ ~ - ~ ~ - ~ He would say "Where's the para
- ~ ~ - ~ ~ - acetamidophenol?"
Ah, I see what you mean now. You want to stress the second syllable, not the first, of acetamido. That's strict. It's not compulsory in [an attempt at] humorous verse, is my view, and my version shouldn't offend a liberal chemist.
>But what I'm mostly curious about is >how that "ff" got in there before "Had". They fell over the edge (as I know you now know).
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Mark Brader - 09 Jul 2009 07:53 GMT Mark Brader:
>> The last line doesn't scan. Paul Wolff:
> - ~ ~ - ~ ~ - > acetamidophenol?" [quoted text clipped - 3 lines] > > It's not compulsory in [an attempt at] humorous verse, is my view, The trouble is that the humor doesn't work if the reader doesn't see what you're getting at. It never occurred to me that you might be imagining accenting the wrong syllable. You needed to write it as "ACetaMIDophenOL" or something.
> and my version shouldn't offend a liberal chemist. I wasn't offended, I just said it didn't scan.
(ObDorothyParker: "Fighting Words".)
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My text in this article is in the public domain.
Paul Wolff - 09 Jul 2009 10:06 GMT >Mark Brader: >>> The last line doesn't scan. [quoted text clipped - 16 lines] > >I wasn't offended, I just said it didn't scan. But are you a liberal chemist?
>(ObDorothyParker: "Fighting Words".) If acetaldehyde is allowed to start with asset...
But never mind that one any more. The paracetamol idea sprang from this old favourite about DDT:
A mosquito was heard to complain That a chemist had poisoned his brain The cause of his sorrow Was paradichloro Diphenyltrichloroethane
which is open to similar criticism, though perhaps less acutely.
 Signature Paul
Adam Funk - 07 Jul 2009 18:46 GMT >> Mind you, you can now get paracetamol and dihydrocodeine OTC - that used >> to be called co-dydramol. I think that's stronger than paracetamol and [quoted text clipped - 3 lines] > and there's a max 5 years for illegal possession. Presumably the > paracetamol must make it unsuitable for non-pain-relief purposes. Is the paracetamol level high enough to make it poisonous for recreational use (along the lines of denatured alcohol)?
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HVS - 07 Jul 2009 15:25 GMT On 07 Jul 2009, Peter Duncanson (BrE) wrote
>>>> On 06 Jul 2009, John Holmes wrote >>>> [quoted text clipped - 55 lines] > Solpadeine tablets are normal strength paracetamol tablets with > added codeine. One has to be careful with codeine -- I can attest that serious constipation is one of its well-documented side effects.
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Default User - 07 Jul 2009 20:28 GMT > One has to be careful with codeine -- I can attest that serious > constipation is one of its well-documented side effects. I was given codeine for the side-effect years back, following abdominal surgery.
Brian
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Garrett Wollman - 07 Jul 2009 21:34 GMT >One has to be careful with codeine -- I can attest that serious >constipation is one of its well-documented side effects. Pretty much all opiates, AFAIK, suppress peristalsis to some degree. That's one of the reasons why they keep you in the hospital after major surgery until you're able to make a successful bowel movement.
-GAWollman
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Paul Wolff - 07 Jul 2009 23:00 GMT >In article <Xns9C419CE78E414whhvans@news.albasani.net>, > [quoted text clipped - 4 lines] >That's one of the reasons why they keep you in the hospital after >major surgery until you're able to make a successful bowel movement. I consider the final movement of Beethoven's seventh symphony to be successful. I'm not sure by what criteria to judge the movements of bowels.
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Garrett Wollman - 07 Jul 2009 23:16 GMT >I consider the final movement of Beethoven's seventh symphony to be >successful. I'm not sure by what criteria to judge the movements of >bowels. I believe, to continue the line of medical euphemism, that a successful bowel movement is one that is "productive".
-GAWollman
 Signature Garrett A. Wollman | The real tragedy of human existence is not that we are wollman@csail.mit.edu| nasty by nature, but that a cruel structural asymmetry Opinions not those | grants to rare events of meanness such power to shape of MIT or CSAIL. | our history. - S.J. Gould, Ten Thousand Acts of Kindness
Chuck Riggs - 08 Jul 2009 10:55 GMT >>>> On 06 Jul 2009, John Holmes wrote >>>> [quoted text clipped - 45 lines] > >In the UK Solpadeine is available OTC but only from pharmacies. Certainly, but my point was that, in America, codeine-based medications are available only with a prescription.
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Chuck Riggs, who speaks AmE, lives near Dublin, Ireland and usually spells in BrE
Hatunen - 08 Jul 2009 23:06 GMT >>In the UK Solpadeine is available OTC but only from pharmacies. > >Certainly, but my point was that, in America, codeine-based >medications are available only with a prescription. Not quite true. In many states you can get codeine cough syrups over the counter, but you must sign a log.
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Chuck Riggs - 09 Jul 2009 15:51 GMT >>>In the UK Solpadeine is available OTC but only from pharmacies. >> [quoted text clipped - 3 lines] >Not quite true. In many states you can get codeine cough syrups >over the counter, but you must sign a log. La-de-dah. No, I'll answer one of Hatunen's silly sticklers seriously for a change: I wouldn't expect an AUE regular, or one of our ilk who does not happen to be a member, to use cough syrup as a pain reliever.
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Regards,
Chuck Riggs, who speaks AmE, lives near Dublin, Ireland and usually spells in BrE
Pat Durkin - 09 Jul 2009 18:05 GMT >>>> In the UK Solpadeine is available OTC but only from pharmacies. >>> [quoted text clipped - 8 lines] > change: I wouldn't expect an AUE regular, or one of our ilk who does > not happen to be a member, to use cough syrup as a pain reliever. Agreed, but that doesn't mean our ilk doesn't have relatives or burglars who might deplete our ilk's supplies in pursuit of some relief for their psychic pain. Just in passing, mind you. I've met a few who indulged in sterno for the same relief.
Chuck Riggs - 10 Jul 2009 15:42 GMT >>>>> In the UK Solpadeine is available OTC but only from pharmacies. >>>> [quoted text clipped - 13 lines] >psychic pain. Just in passing, mind you. I've met a few who indulged >in sterno for the same relief. As I'm relatively safe from burglars and my relatives are safely in America, I had not thought of that. Thank you for my best laugh of the day, Pat.
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Regards,
Chuck Riggs, who speaks AmE, lives near Dublin, Ireland and usually spells in BrE
Robert Bannister - 10 Jul 2009 01:34 GMT >>>> In the UK Solpadeine is available OTC but only from pharmacies. >>> Certainly, but my point was that, in America, codeine-based [quoted text clipped - 6 lines] > change: I wouldn't expect an AUE regular, or one of our ilk who does > not happen to be a member, to use cough syrup as a pain reliever. Come to think of it, an awful lot of cough medicines contain quite large amounts of alcohol, so it's not to be sniffed at.
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Chuck Riggs - 10 Jul 2009 15:47 GMT >>>>> In the UK Solpadeine is available OTC but only from pharmacies. >>>> Certainly, but my point was that, in America, codeine-based [quoted text clipped - 9 lines] >Come to think of it, an awful lot of cough medicines contain quite large >amounts of alcohol, so it's not to be sniffed at. Mine tastes good too, but Shirley beer, especially at today's bargain prices, is a good deal cheaper
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Regards,
Chuck Riggs, who speaks AmE, lives near Dublin, Ireland and usually spells in BrE
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